Various Chromatographic Schemes for Separation of 213Bi from 225Ac
نویسندگان
چکیده
منابع مشابه
Targeted Alpha-Particle Immunotherapy with Bismuth-213 and Actinium-225 for Acute Myeloid Leukemia
Lintuzumab, a humanized anti-CD33 antibody, targets myeloid leukemia cells and has modest activity against acute myeloid leukemia (AML). To increase the antibody’s potency yet avoid nonspecific cytotoxicity seen with -emitting isotopes, lintuzumab was conjugated to the -emitters bismuth-213 (213Bi) and actinium-225 (225Ac). The 46-minute half-life of 213Bi limits its widespread use. Therefore...
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ژورنال
عنوان ژورنال: Journal of Medical Imaging and Radiation Sciences
سال: 2019
ISSN: 1939-8654
DOI: 10.1016/j.jmir.2019.03.067